Formulations of vesicant drugs and methods of use thereof
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United States of America Patent
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Jul 14, 1998
Grant Date -
N/A
app pub date -
Jul 9, 1996
filing date -
Jul 9, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to methods of treating, as well as preventing extravasation injury. In particular, the present invention pertains to photochemotherapeutic methods of prophylaxis and/or treatment of extravasation injury induced by vesicant antineoplastic drugs and other pharmaceutical formulations. In accordance with the present invention, extravasation injury is prevented or minimized by the coadministration of photoinactivation inducing compounds in a formulation comprising a vesicant antineoplastic or other pharmaceutical formulation, and subsequently exposing the injection or infusion site to photoexciting light.
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