C-reactive protein fragment with immunomodulatory activity

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United States of America Patent

PATENT NO 5783179
SERIAL NO

07743613

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds having immunomodulatory activity comprising the optionally modified dodecapeptide fragment A-(SEQ ID No: 1)-B corresponding to residues 174 to 185 of C-reactive protein (CRP), pharmaceutical compositions thereof, and methods of treating cancer with the compositions. Liposomal formulations containing the CRP-peptide fragment are particularly efficacious when administered in conjunction with interleukin-2.

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Patent Owner(s)

  • SYNTEX (U.S.A.) INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barna, Barbara P Berea, OH 1 31
Deodhar, Sharad D Shaker Heights, OH 1 31
Eppstein, Deborah A Palo Alto, CA 18 3947
Felgner, Philip L San Diego, CA 49 5868
Ho, Teresa H Los Altos, CA 7 258
Nestor, Jr John J Cupertino, CA 17 559

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