Antibody-induced apoptosis

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United States of America Patent

PATENT NO 5783186
SERIAL NO

08568072

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Anti-Her2 antibodies which induce apoptosis in Her2 expressing cells are disclosed. The antibodies are used to 'tag' Her2 overexpressing tumors for elimination by the host immune system. Also disclosed are hybridoma cell lines producing the antibodies, methods for treating cancer using the antibodies, and pharmaceutical compositions.

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Patent Owner(s)

Patent OwnerAddress
AMGEN INCONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arakawa, Tsutomu Thousand Oaks, CA 37 896
Kita, Yoshiko Thousand Oaks, CA 8 246

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