Assays and devices for distinguishing between normal and abnormal pregnancy
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United States of America Patent
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Jul 28, 1998
Grant Date -
N/A
app pub date -
Apr 28, 1995
filing date -
Apr 28, 1995
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Methods and devices for distinguishing between normal and abnormal pregnancies are provided. The methods rely on determining the concentration of progesterone or progesterone metabolite in a patient sample, where a concentration above a threshold value is indicative of a normal pregnancy. Preferably, the concentration of hCG is determined simultaneously, where an hCG concentration above a threshold value provides confirmation that the individual being tested is pregnant. An exemplary test device comprises a lateral flow membrane having zones for capturing label in response to the progesterone and hCG concentrations, respectively. Visible label is accumulated when the hCG concentration exceeds the threshold value but is absent when the progesterone concentration exceeds the threshold value.
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Family
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