US Patent No: 5,789,462

Number of patents in Portfolio can not be more than 2000

Photocured crosslinked-hyaluronic acid contact lens

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Abstract

A photocured crosslinked-hyaluronic acid contact lens which comprises a photocured crosslinked-hyaluronic acid derivative produced by the formation of a crosslinked cyclobutane ring by light irradiation from mutual photoreactive crosslinking groups of a photoreactive hyaluronic acid derivative in which the photoreactive crosslinking groups are linked to hyaluronic acid, wherein the photoreactive crosslinking groups are introduced into functional groups of hyaluronic acid via a spacer group, and the contact lens has a water content of 80 to 99% and shape compatibility and tissue affinity for the eyeball. A process for preparing a photocured crosslinked-hyaluronic acid contact lens which comprises molding the photoreactive hyaluronic acid derivative into a shape that fits to the eyeball, and subsequently irradiating the shaped product with light to effect crosslinking between the mutual photoreactive crosslinking groups.

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First Claim

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Patent Owner(s)

Patent OwnerAddressTotal Patents
SEIKAGAKU CORPORATIONTOKYO178

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Miyauchi, Satoshi Tokyo, JP 14 56
Motani, Yoshihiro Tokyo, JP 3 24

Cited Art

Patent Info (Count) # Cites Year
 
MDV TECHNOLOGIES, INC. (3)
5,143,731 Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels 51 1990
5,277,911 Ablatable mask of polyoxyalkylene polymer and ionic polysaccharide gel for laser reprofiling of the cornea 31 1990
5,376,693 Thermo-irreversible gel corneal contact lens formed in situ 21 1990
 
VISION 2000 TECHNOLOGIES, INC. (3)
4,223,984 Collagen soft contact lens 40 1979
4,264,155 Collagen contact lens 51 1979
4,260,228 Collagen gel contact lens and method of preparation 29 1980
 
CIBA VISION CORPORATION (1)
5,527,925 Functionalized photoinitiators, macromers thereof, and the use thereof 40 1994
 
COLLAGEN AESTHETICS, INC. (1)
5,510,418 Glycosaminoglycan-synthetic polymer conjugates 96 1993
 
SEIKAGAKU CORPORATION (1)
5,462,976 Photocurable glycosaminoglycan derivatives, crosslinked glycosaminoglycans and method of production thereof 31 1993
 
UNIVERSITY OF WASHINGTON (1)
4,532,267 Vision correction lens made from an aminopolysaccharide compound or an ether or ester thereof 15 1984

Patent Citation Ranking

Forward Cites

Patent Info (Count) # Cites Year
 
SEIKAGAKU CORPORATION (6)
6,602,859 Photocurable hyaluronic acid derivative and process for producing the same, and photocured crosslinked-hyaluronic acid derivative and medical material using the same 6 2001
7,893,225 Crosslinked polysaccharide sponge 0 2002
8,071,756 Polysaccharide pseudo-sponge 1 2004
7,951,936 Crosslinked polysaccharide sponge 0 2007
7,700,747 Crosslinked polysaccharide sponge 0 2007
8,389,713 Polysaccharide pseudo-sponge 0 2011
 
CANON KABUSHIKI KAISHA (1)
6,825,979 Optical system having a diffractive optical element, and optical apparatus 5 2002
 
JOHNSON & JOHNSON VISION CARE, INC. (1)
7,118,213 Promotional aid 1 2004
 
OTHER [CHECK PATENT PROFILE FOR ASSIGNMENT INFORMATION] (1)
7,674,781 Hyaluronic acid-retaining polymers 0 2007