Multi-reactor synthesizer and method for combinatorial chemistry
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United States of America Patent
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Aug 11, 1998
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N/A
app pub date -
May 30, 1996
filing date -
May 30, 1996
priority date (Note) -
Expired
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Abstract
Solid phase combinatorial synthesis is carried out in a multi-reactor synthesizer comprising an array of separate reactor cells containing a solid reaction support medium. Subsets of reactor cells are interconnected with one another in a desired pattern, and, in a first reaction step, reagents are circulated through the subsets. After the first reaction step is completed, the reactor cells are rearranged into a new configuration of subsets, and the same, or other, reagents are circulated through the new subsets. The process can be repeated to produce large numbers of compounds differing from one another.
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