Analogues of magainin peptides containing D-amino acids
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United States of America Patent
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Aug 11, 1998
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Nov 17, 1994
filing date -
Feb 8, 1990
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Abstract
Biologically active analogues of magainin peptides wherein each amino acid residue of the peptide is a D-amino acid residue or a glycine residue. Examples of such peptides wherein each amino acid residue is a D-amino acid residue or a glycine residue include deletion and substitution analogues of magainin peptides. Such peptides have increased resistance to proteolytic enzymes while retaining biological activity.
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