Methods for the assay of troponin I and T and selection of antibodies for use in immunoassays
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United States of America Patent
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Aug 18, 1998
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N/A
app pub date -
Apr 18, 1995
filing date -
Apr 18, 1995
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Abstract
Assays and antibodies are disclosed for the detection and quantitation of cardiac specific troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in various conformations in the blood, the ratios of the monomeric troponin I and T and the binary and ternary complexes may be related to the metabolic state of the heart. More specifically, immunoassays for determining the presence or amount of free, binary and ternary complexes of troponin I and T are claimed.
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