Therapeutic methods of using O-desulfated heparin derivatives
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United States of America Patent
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Aug 18, 1998
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Jan 9, 1997
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May 6, 1994
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Abstract
Compositions and methods of making selectively O-desulfated heparin compositions, preferably 6-O-desulfated heparin compositions, wherein the methods permit regulating the degree of 6-O-desulfation. The compositions are useful for treating various diseases, including cancer, angiogenesis, shock, ischemia reperfusion injury, inflammation, and cardiovascular diseases including restenosis.
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