Method of culturing micro-organisms under a mutagenic influence

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United States of America Patent

PATENT NO 5798253
SERIAL NO

08704749

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Abstract

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An accelerated micro-organism culture method is for decomposing harmful substances. For this purpose, the cultivation, mutagenic treatment and stabilization of the micro-organisms are carried out simultaneously in a mutation fermenter containing a nutrient-rich basic medium (basic medium 1); selection is carried out in a selection fermenter containing a basic medium which is low in nutrients and is enriched with the harmful substance (basic medium 2); small amounts of biomass released from the nutrient-rich basic medium (basic medium 1) of the mutation fermenter are continuously removed from the mutation fermenter and transferred to the selection fermenter. Small amounts of biomass released from the basic medium which is low in nutrients (basic medium 2) of the selection fermenter are removed from the selection fermenter and transferred to the mutation fermenter. The entire process is carried out continuously in alternating selection and mutation phases, in the manner of a repeated cycle. The mutation fermenter and the selection fermenter are associated with computerized control circuits by means of which the fermentation parameters can be adjusted independently of one another in both fermenters.

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Patent Owner(s)

Patent OwnerAddress
RUSSELL CORPORATION3330 CUMBERLAND BLVD SUITE 800 ATLANTA GA 30339

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bartholmes, Peter Witten, DE 2 16
Kaufmann, Michael Dortmund, DE 74 571
Schwarz, Thomas Leichlingen, DE 258 1343

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