Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
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United States of America Patent
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Sep 1, 1998
Issued Date -
N/A
app pub date -
Jan 10, 1994
filing date -
Apr 25, 1991
priority date (Note) -
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Abstract
Immunoisolatory vehicles having a core and a surrounding jacket are disclosed, the core having a volume in excess of 1 .mu.l and at least about 10.sup.4 living cells capable of secreting a biologically active product or of providing a biological function to a patient, the cells dispersed in a biocompatible matrix formed of a hydrogel or an extracellular matrix component, and the external jacket being permselective, biocompatible and having a molecular weight cutoff permitting passage of molecules between the patient and the core through said jacket to provide said biological product or function.
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