Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases

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United States of America Patent

PATENT NO 5801175
SERIAL NO

08713324

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Abstract

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Novel compounds of Formula ##STR1## are disclosed. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering a compound of the above formula to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human being.

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Patent Owner(s)

Patent OwnerAddress
PHARMACOPEIA DRUG DISCOVERY3000 PARK BOULEVARD CRANBURY NJ 08512

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Afonso, Adriano West Caldwell, NJ 42 603
Baldwin, John J Gwynedd Valley, PA 214 2088
Doll, Ronald J Maplewood, NJ 120 1796
Li, Ge Franklin Park, NJ 125 1180
Mallams, Alan K Long Valley, NJ 51 732
Njoroge, F George Union, NJ 117 2490
Rane, Dinanath F Morganville, NJ 28 443
Reader, John C Princeton, NJ 21 1316
Rossman, Randall R Nutley, NJ 9 194

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