Compositions and methods for immunosuppressing

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United States of America Patent

PATENT NO 5801193
SERIAL NO

08843401

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Abstract

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Methods and compounds for inducing immunosuppression in animals which need immunosuppressive treatment involving administration to animals of a therapeutically effective amount of a compound of the following formula ##STR1## where R is H, PO.sub.3.sup.=, alkyl of 1 to 12 carbon atoms substituted or unsubstituted, straight chain or branched, 0 to 6 double bonds, (CH.sub.2).sub.n morpholine where n=1-4, morpholinomethylphenyl, orthoaminophenyl, orthohydroxyphenyl, (CH.sub.2).sub.n COOR.sub.2 where n=1-4 where R.sub.2 is H, an alkalai metal salt, an alkaline earth metal salt, NH.sub.4.sup.+, N.sup.+ (R.sub.3).sub.4 where R.sub.3 is independently selected from the group consisting of H and alkyl of 1 to 4 carbon atoms, COR.sub.1 wherein R.sub.1 is selected from the group consisting of H, (CH.sub.2).sub.n CH.sub.3, where n=1-6, (CH.sub.2).sub.n COOR.sub.2 where n=1-4 and R.sub.2 is previously defined, (CH.sub.2).sub.n N.sup.+ (R.sub.3).sub.4 wherein n=1-4, and (CH.sub.2).sub.n SO.sub.3.sup.- where N=1-4, and pharmaceutically acceptable salts thereof.

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Patent Owner(s)

Patent OwnerAddress
IMMUNE MODULATIONS INC2211 MICHIGAN AVENUE SANTA MONICA CA 90404

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cottam, Howard B Fallbrook, CA 52 718
Ojo-Amaize, Emmanuel A Glendora, CA 11 65
Okogun, Joseph I New Rochelle, NY 4 54

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