Compositions comprising leukocyte-derived growth factors and methods of administering same to facilitate wound healing
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United States of America Patent
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Sep 8, 1998
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app pub date -
Apr 4, 1995
filing date -
Feb 1, 1990
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Abstract
A gene encoding a leukocyte-derived growth factor (LDGF) has been isolated, cloned and sequenced. LDGF is believed to correspond to a PDGF-like monocyte-derived growth factor with chemotactic activity which is found in human wound fluid. Protease-resistant and other analogues of LDGF, as well as recombinant LDGF of native amino acid sequence, may now be produced by gene expression in transformed hosts.
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