Exocylic-phosphoethanolamines
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United States of America Patent
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Sep 8, 1998
Grant Date -
N/A
app pub date -
Mar 14, 1997
filing date -
Mar 14, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Disclosed are the use of certain cycloalkyl- and aryl-phosphoethanolamines as anti-inflammatory, anti-arrhythmic and local anesthetic agents. These therapeutically active cycloalkyl- and aryl-phosphoethanolamines are of the general Formula I: R--O--PEA I wherein R is an unsubstituted or a substituted C.sub.5-7 cycloalkyl or an unsubstituted or a substituted phenyl in which each substituent is hydrogen or an unsubstituted or substituted straight or branched C.sub.1-4 alkyl or C.sub.2-4 alkenyl, said substitution being one or more of C.sub.1-4 alkoxy, halo or cyano; and --O--PEA represents a phosphoethanolamine substituent. Also disclosed are intermediates for producing Formula I compounds.
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