.alpha.-Amino sulfonyl hydroxamic acids as matrix metalloproteinase inhibitors

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United States of America Patent

PATENT NO 5804593
SERIAL NO

08953940

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Abstract

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A compound of formula I or pharmaceutical acceptable salts thereof, ##STR1## wherein R.sub.1 is isopropyl, 2-methylbut-2yl, phenyl, benzyl, or 1H-indol-3ylmethyl; R.sub.2 is n-octyl, phenyl, or phenyl substituted with methoxy, fluoro, or bromo, are matrix metalloproteinase inhibitors.

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Patent Owner(s)

Patent OwnerAddress
PHARMACIA & UPJOHN COMPANY301 HENRIETTA STREET KALAMAZOO MI 49001 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jacobsen, Eric Jon Portage, MI 65 658
Mitchell, Mark Allen Kalamazoo, MI 5 76
Warpehoski, Martha A Portage, MI 14 376

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