Process for the preparation of sustained release pellets
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United States of America Patent
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Sep 15, 1998
Grant Date -
N/A
app pub date -
Jan 12, 1995
filing date -
Mar 20, 1992
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
A process for the manufacture of sustained release pellets comprising pelletizing a mixture containing the drug in finely divided form and a binder. The characteristic feature is that: (a) said binder is in particle form consisting of one or more water-insoluble wax-like binder substance(s) with a melting point above 40.degree. C., and (b) said pelletization step is performed by mechanically working said mixture, in a high shear mixer, under the input of a sufficient amount of energy for the binder to melt and pelletization to take place.
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