Polyiodinated compounds, their preparation and their use as contrast media for radiology
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United States of America Patent
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Oct 6, 1998
Grant Date -
N/A
app pub date -
Nov 1, 1994
filing date -
Mar 22, 1993
priority date (Note) -
Expired
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Abstract
The present invention relates to polyiodinated compounds with a single molecular weight having a molecular concentration of iodine of greater than approximately 20% by weight, and in particular greater than approximately 30% by weight, containing at least 9 iodine atoms and having a molecular weight above 2000 and below approximately 50,000, and in particular above 2000 and below approximately 20,000, said compounds possessing either a zero overall electrical charge or at least two anionic charges, and persisting in the vascular compartment at a value equal to at least approximately 30% by weight of the injected dose in a subject five minutes after intravascular administration in the said subject.
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