Photochemistry for the preparation of biologic grafts--allografts and xenografts

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United States of America Patent

PATENT NO 5824080
SERIAL NO

08708376

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Abstract

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Photodynamic therapy (PDT), a technique to produce cytotoxic free radicals, was used to prepare arterial allografts. After impregnation with the photo-sensitizer chloroaluminum sulfonated phthalocyanine, aortas of ACI rats were PDT-treated and transplanted in Lewis rats. PDT grafts were completely reendothelialized by 4 weeks.

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Patent Owner(s)

Patent OwnerAddress
GENERAL HOSPITAL CORPORATION THE55 FRUIT STREET BOSTON MA 02114

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lamuraglia, Glenn M Winchester, MA 1 99

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