Microparticulate microbubble-generating contrast agents
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United States of America Patent
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Oct 27, 1998
Issued Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Jan 9, 1992
priority date (Note) -
Expired
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Abstract
The present invention relates to contrast agents comprising microbubble-generating carbohydrate particles having a surfactant admixed within the microparticulate structure, wherein the microbubbles generated by the microparticles comprise a biocompatible low molecular weight fluorinated hydrocarbon. The contrast agents exhibit useful levels of contrast efficiency and/or stability and may be used in diagnostic applications such as ultrasound and MR imaging.
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