In situ recombinant PCR within single cells
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United States of America Patent
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Nov 3, 1998
Grant Date -
N/A
app pub date -
Jul 13, 1994
filing date -
Aug 10, 1991
priority date (Note) -
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Abstract
Disclosed is a method of treating a heterogeneous population of cells to link together copies of two or more nucleic acid sequences from at least some of the cells, the arrangement being such that copies of the DNA sequences from an individual cell are preferentially linked in the vicinity of the nucleic acid from which the copies are derived. Also disclosed are recombinant proteins expressed by the method of the invention and kits for performing said method.
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