Formation of triple helix complexes of single stranded nucleic acids using nucleoside oligomers which comprise pyrimidine analogs, triple helix complexes formed thereby and oligomers used in their formation
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United States of America Patent
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Nov 10, 1998
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N/A
app pub date -
Nov 21, 1994
filing date -
Oct 28, 1986
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Expired
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Abstract
Methods of detecting, recognizing or inhibiting or altering expression of a target sequence of a single stranded nucleic acid having any combination of purine and pyrimidine nucleosides by formation of triple helix complexes in conjunction with Second and Third Strands which comprise optionally covalently linked Oligomers are provided.
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