Process for the preparation of D-.alpha.-amino acids
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United States of America Patent
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Nov 10, 1998
Grant Date -
N/A
app pub date -
Nov 6, 1996
filing date -
Nov 23, 1995
priority date (Note) -
Expired
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Abstract
In an improved process for the preparation of D-.alpha.-amino acids by the stereoselective conversion of racemic mixtures of 5-substituted hydantoins with an enzymatic system produced by a microorganism, the improvement consists in the fact that a microorganism is used which is transformed with the plasmid pSM700 cultivated at a temperature of between 20.degree. C. and 28.degree. C. The use of this microorganism allows an improvement in the expression of the enzymatic system and an increase in the conversion rate of the racemic hydantoin to D-.alpha.-amino acid.
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