Glucose concentration measuring method and apparatus with short coherence source and heterodyne interferometer

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United States of America Patent

PATENT NO 5835215
SERIAL NO

08857205

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Abstract

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A low coherence light beam is irradiated to the eyeball. A backward scattered light beam, which is reflected from each depth position in the eyeball, and a reference light beam, which is reflected from a mirror capable of moving, are caused to interfere with each other. A first backward scattered light beam, which comes from the interface between the cornea and the anterior aqueous chamber, and a second backward scattered light beam, which comes from the interface between the anterior aqueous chamber and the crystalline lens, are thus separated accurately from each other. An optical absorbance of the anterior aqueous chamber (the aqueous humor) is calculated from the intensities of the two backward scattered light beams. Each of a plurality of low coherence light beams having different wavelengths is irradiated to the eyeball, and the aforesaid operation is repeated. The concentration of glucose in the aqueous humor is measured by utilizing near-infrared spectroscopy. The measurement is thus achieved non-invasively and accurately.

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Patent Owner(s)

Patent OwnerAddress
FUJIFILM CORPORATIONTOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Miyagawa, Ichirou Kanagawa-ken, JP 67 654
Toida, Masahiro Kanagawa-ken, JP 48 2225

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