Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis

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United States of America Patent

PATENT NO 5837680
SERIAL NO

08602941

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to pharmaceutical compositions containing troponin subunits C, I, or T, or fragments thereof, in therapeutically effective amounts that are capable of inhibiting endothelial cell proliferation. The invention also relates to pharmaceutical compositions containing analogs of troponin subunits C, I, or T and analogs of their fragments, in therapeutically effective amounts that are capable of inhibiting endothelial cell proliferation. The invention further relates to treatment of neovascular disorders by administration of a therapeutic compound of the invention.

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Patent Owner(s)

Patent OwnerAddress
CHILDREN'S MEDICAL CENTER CORPORATION55 SHATTUCK STREET BOSTON MA 02115

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Langer, Robert S Newton, MA 635 37250
Moses, Marsha A Brookline, MA 58 448
Sytkowski, Arthur Arlington, MA 4 90
Wiederschain, Dimitri G Brookline, MA 4 90
Wu, Inmin Boston, MA 5 92

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