Sialyl lewis-x mimetics containing naphthyl backbones
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United States of America Patent
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Nov 17, 1998
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app pub date -
Feb 21, 1996
filing date -
Jun 16, 1993
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Expired
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Abstract
Compounds that possess selectin binding activity are described that have a three-dimensionally stable configuration for sialic acid and fucose, or analogs, derivatives, or mimics of these groups, such that sialic acid and fucose or their mimics are separated by a linker that permits binding between those groups and the selecting, such compounds being represented by the following general structural formula I: ##STR1##
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