Methods and bicyclic polyamine compositions for the treatment of inflammation
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United States of America Patent
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Dec 1, 1998
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app pub date -
Mar 19, 1997
filing date -
Mar 19, 1997
priority date (Note) -
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Abstract
Methods for treating inflammatory conditions wherein the active agent is a polyamine having the formula set forth below: ##STR1## or a salt thereof with a pharmaceutically acceptable acid wherein: R.sub.1, R.sub.2, R.sub.3 and R.sub.4 may be the same or different and represent H, straight- or branched-chain alkyl, aryl, aryl alkyl or cycloalkyl of 1-12 carbon atoms; a, b, c and d may be the same or different and are integers from 0 to 8, except that when a or c is zero, b or d is greater than or equal to 3 and when a or c is one, b or d is greater than or equal to 2; and X, Y and Z may be the same or different; X and Z are integers from 0 to 10; and Y is an integer from 1 to 10, excluding the polyamine of the formula wherein a=b=c=d=2, X=Z=2 and Y=4.
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