Compositions and methods for altering the biodistribution of biological agents
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United States of America Patent
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Dec 15, 1998
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N/A
app pub date -
Jun 28, 1996
filing date -
Jun 28, 1996
priority date (Note) -
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Abstract
This invention relates to a new and improved pharmaceutical composition and method for delivery of therapeutic or bioactive agents. The methods and composition of the invention can be used with several therapeutic or bioactive agents and can achieve site-specific delivery of a therapeutic or biologically-active substance. This can allow for lower doses and for improved efficacy with drugs, particularly agents such as oligonucleotides which are plagued with problems in achieving therapeutic levels at targeted sites.
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