Rapid detection of antibiotic resistance in mycobacterium tuberculosis

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United States of America Patent

PATENT NO 5851763
SERIAL NO

08313185

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Abstract

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A process for the detection of resistance to an antibiotic in a mycobacterium comprises detecting a mutation in a gene selected from the group consisting of the katG gene or fragment thereof, the rpoB gene or fragment thereof, and the rpsI gene or fragment thereof. The process is useful for detecting in vitro the presence of nucleic acids of a Mycobacterium tuberculosis resistant to isoniazid.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT PASTEURPARIS FRANCE PARIS PARIS
ASSISTANCE PUBLIQUE3 AVE A FRENCH BODY CORP VICTORIA - 75100 PARIS
UNIVERSITE DE BERNEHOCHSCHULSTRASSE 4 CH-3012 BERNE
MEDICAL RESEARCH COUNCIIL20 PARK CRESCENT LONDON W1N 4
UNIVERSITE PIERRE ET MARIE CURIE (PARIS V1)4 PLACE JUSSIEU 75252 PARIS CEDEX 05

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bodmer, Thomas Ersigen, CH 2 21
Cole, Stewart Clamart, FR 35 292
Heym, Beate Ville d'Avray, FR 4 31
Honore, Nadine Colombes, FR 4 48
Telenti, Amalio Gerzensee, CH 18 127
Young, Douglas Ruislip, GB 20 227
Zhang, Ying London, GB 923 12176

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