Preparation of chlorinated paclitaxel analogues and use thereof as antitumor agents
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United States of America Patent
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Dec 29, 1998
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May 29, 1996
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Dec 13, 1995
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Abstract
Provided are novel paclitaxel analogues which are selectively chlorinated stereospecific derivatives of cephalomannine and 7-epi-cephalomannine having paclitaxel-like antitumor efficacy, methods for their preparation and methods for treating tumors with these compounds.
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