3-benzoyl benzofuran derivatives as thyroid hormone antagonists

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United States of America Patent

PATENT NO 5854282
SERIAL NO

08776924

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention provides compounds according to the formula ##STR1## in which: Ha=I or Br X=CH.sub.2 or C=O R.sup.1 =C.sub.1-4 alkyl R.sup.2 =--NHSO.sub.2 R.sup.3 ; --NHCOR.sup.3 ; or --NHCONHR.sup.3 where R.sup.3 =--CF.sub.3,C.sub.1-3 alkyl, 4-R.sup.4 C.sub.6 H.sub.4 --; where R.sup.4 =C.sub.1-4 alkoxy-; hydroxy-; fluoro-; or nitro-; or a pharmaceutically acceptable salt thereof. The compounds may particularly be used in the treatment of T3 regulated gene disorders and diseases.

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Patent Owner(s)

  • KARO BIO AB

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mellin, Charlotta Tullinge, SE 2 24

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