Granules having core and their production
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United States of America Patent
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Jan 5, 1999
Issued Date -
N/A
app pub date -
Aug 9, 1994
filing date -
Sep 27, 1988
priority date (Note) -
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Abstract
Granules having a core are produced by spraying core granules with a dispersion of a low substituted hydroxypropylcellulose (L-HPC), and, if necessary, simultaneously applying a dusting powder. The granules having a core thus obtained exhibit increased granule strength and improved disintegrating property as compared with those produced by known methods. An active ingredient such as a drug can be contained in the dispersion, dusting powder or core granules.
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