Hydrolyzed cellulose granulations for pharmaceuticals
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United States of America Patent
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Jan 12, 1999
Grant Date -
N/A
app pub date -
Apr 17, 1996
filing date -
Apr 17, 1996
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention provides a method for preparing a spray-dried compressible granular formulation for preparing pharmaceutical tablets in which hydrolyzed cellulose is used as a granulation aid, the resulting granulations, and pharmaceutical tablets compressed from such granules. In these formulations there is employed from 1 to 97% by weight pharmaceutical active, from about 3 to 99% by weight hydrolyzed cellulose, based on the dry weight of the granulation, and optionally conventional granulation and/or tableting additives such as surfactants, disintegrants and antiadherents/flow aids.
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