Aggregate angiostatin and method of use

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United States of America Patent

PATENT NO 5861372
SERIAL NO

08605598

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention comprises an aggregate endothelial inhibitor and method of use therefor. The aggregate endothelial inhibitor comprises a protein having a molecular weight of between approximately 45 kilodaltons and 65 kilodaltons as determined by reducing polyacrylamide gel electrophoresis, and having an amino acid sequence substantially similar to that of a murine plasminogen fragment beginning at amino acid number 98 of a murine plasminogen molecule.

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Patent Owner(s)

Patent OwnerAddress
CHILDREN'S MEDICAL CENTER CORPORATION THE55 SHATTUCK STREET BOSTON MA 02115

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Folkman, M Judah Brookline, MA 39 864
Lin, Jie Newton Center, MA 159 1294
O'Reilly, Michael S Winchester, MA 36 853

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