Pharmaceutical composition for the treatment of a malignant tumor
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United States of America Patent
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Jan 19, 1999
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N/A
app pub date -
Jun 7, 1995
filing date -
Oct 23, 1990
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Abstract
A pharmaceutical composition which comprises a recombinant vaccinia virus containing a DNA fragment encoding for a polypeptide recognized by a particular antibody H23, which recognizes a particular tumor antigen expressed on breast cancer cells is provided. The antibody specifically binds to an epitope comprising a tandem repeat sequence of 20 amino acids comprised in a transmembrane form as well as a secreted form of the POLYPEPTIDES specifically bound by antibody H23.
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