Factor VIIa inhibitors from kunitz domain proteins

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United States of America Patent

PATENT NO 5863893
SERIAL NO

08398628

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Abstract

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A potent serine protease inhibitor capable of inhibiting Factor VIIa, Factor XIa, plasma kallikrein, or plasmin is provided. The inhibitor is provided in a pharmaceutical composition for treatment of diseases where inhibition of Factor VIIa, Factor XIa, plasma kallikrein, or plasmin is indicated.

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Patent Owner(s)

Patent OwnerAddress
GENENTECH INC1 DNA WAY SOUTH SAN FRANCISCO CA 94080-4990

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dennis, Mark S San Carlos, CA 111 2042
Lazarus, Robert A Millbrae, CA 49 801

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