Precision and accuracy of anion-exchange separation of nucleic acids

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 5866429
SERIAL NO

08515885

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Solvents for salt-gradient anion-exchange separation of nucleic acids, especially double-stranded DNA and especially by liquid chromatography, are improved by replacing NaCl as the eluting salt with any of a wide range of alkyl ammonium salts and can be used to elute nucleic acids in strict order of increasing length, with reduced sensitivity to elution temperature and salt concentration. Anion-exchange chromatography with these solvents is well suited for identification of DNA fragments on the basis of size, with greater accuracy, precision, and resolvable size range than often is possible with gel electrophoresis.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
APPLIED BIOSYSTEMS LLC850 LINCOLN CENTRE DRIVE FOSTER CITY CA 94404

International Classification(s)

  • [Classification Symbol]
  • [Patents Count]

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bloch, Will 607 N. Claremont St., #A, San Mateo, CA 94401 32 1913

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation