Graphitic nanotubes in luminescence assays

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United States of America Patent

PATENT NO 5866434
SERIAL NO

08611347

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Abstract

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Graphitic nanotubes, which include tubular fullerenes (commonly called 'buckytubes') and fibrils, which are functionalized by chemical substitution, are used as solid supports in electrogenerated chemiluminescence assays. The graphitic nanotubes are chemically modified with functional group biomolecules prior to use in an assay. Association of electrochemiluminescent ruthenium complexes with the functional group biomolecule-modified nanotubes permits detection of molecules including nucleic acids, antigens, enzymes, and enzyme substrates by multiple formats.

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Patent Owner(s)

Patent OwnerAddress
MESO SCALE TECHNOLOGIES LLC1601 RESEARCH BOULEVARD ROCKVI MD 20850

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dong, Liwen Rockville, MD 63 595
Fischer, Alan Cambridge, MD 47 2486
Hoch, Robert Hensonville, NY 69 2188
Jameison, Fabian Gaithersburg, MD 7 432
Leland, Jonathan K Silver Spring, MD 52 2235
Liang, Pam Rockville, MD 12 496
Lu, Ming Lanham, MD 165 2049
Martin, Mark T Bethesda, MD 44 898
Massey, Richard J Rockville, MD 48 1255

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