Methods and compositions for inducing complement destruction of tissue

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United States of America Patent

PATENT NO 5869035
SERIAL NO

08748344

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Abstract

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The invention discloses methods and compositions for killing tumor cells in animals. Through transfer techniques, cancer cells are engineered to express an epitope which is targeted by natural antibodies causing complement destruction of transformed tumor cells that is typically associated with hyperacute xenograft rejection.

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Patent Owner(s)

Patent OwnerAddress
HUMAN GENE THERAPY RESEARCH INSTITUTEDES MOINES IA 50309

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Levy, John P West Des Moines, IA 12 53
Link, Jr Charles J Clive, IA 11 98

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