Human platelet-derived growth factor receptor extracellular domain antibodies
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United States of America Patent
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Feb 16, 1999
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N/A
app pub date -
Jun 2, 1995
filing date -
Jan 31, 1991
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Abstract
This invention provides antibodies that bind to epitopes of human platelet-derived growth factor receptor (hPDGF-R) fragments, wherein the fragments comprise one or more platelet-derived growth factor (PDGF) ligand binding regions from extracellular domains D1, D2, and D3. Also provided are antibodies specific for domain D3, such as monoclonal antibodies directed to the intra-cysteine portion of domain D3.
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