US Patent No: 5,872,359

Number of patents in Portfolio can not be more than 2000

Real-time monitor and control system and method for hydrogen peroxide vapor decontamination

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Abstract

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The invention includes a system and a method for maintaining a selected concentration of a sterilant vapor during vapor phase sterilization. The system includes a sterilization chamber with a source of multicomponent vapor containing a sterilant vapor, an electromagnetic radiation source capable of generating radiation at a plurality of wavelengths, a radiation detector for detecting and quantitating the electromagnetic radiation absorbed at the wavelengths, the detector generating absorbance signals proportional to the concentration of the sterilant vapor in the multicomponent vapor, a microprocessor programmed to compare the absorbance signals with reference absorbance signals, to calculate the sterilant vapor concentration therefrom and to generate an output signal, and a controller to receive the output signal and to control addition of the sterilant vapor to the sterilization chamber to maintain a selected concentration of the sterilant vapor in the sterilization chamber during the sterilization process. The method allows sterilization conditions to be optimized to reduce the time required for and to increase the sterilization efficacy of the sterilization procedure.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
AMERICAN STERILIZER COMPANYMENTOR, OH390

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Sparber, George Broadway, NC 1 35
Stewart, Bonnie Durham, NC 2 84
Zell, Peter Raleigh, NC 2 97

Cited Art Landscape

Patent Info (Count) # Cites Year
 
AMERICAN STERILIZER COMPANY (7)
4,843,867 System for monitoring sterilant vapor concentration 40 1987
4,956,145 Optimum hydrogen peroxide vapor sterilization method 82 1987
RE33007 Method of vaporizing multicomponent liquids 21 1988
4,909,999 Flow-through vapor phase sterilization system 68 1989
5,173,258 Recirculation, vapor and humidity control in a sealable enclosure 50 1989
5,139,957 Chemical indicator that includes potassium dichromate and urea and method of using the same to detect hydrogen peroxide 25 1990
5,600,142 Measurement of vaporized hydrogen peroxide 49 1995
 
GUIDED WAVE, INC. (3)
4,664,522 Optical waveguide spectrum analyzer and method 23 1984
4,786,171 Spectral analysis apparatus and method 39 1986
5,184,193 Dual fiber optic spectrophotometer 8 1989
 
Detector Electronics Corporation (1)
5,475,222 Ruggedized gas detector 9 1994
 
ENVIROTEST SYSTEMS HOLDINGS CORP. (1)
5,418,366 IR-based nitric oxide sensor having water vapor compensation 52 1994
 
FIAtron-Eppendorf, Inc. (1)
5,139,956 Method and system for determining peroxide content 10 1991
 
GAS RESEARCH INSTITUTE (1)
5,055,690 Method of eliminating water vapor interference in detecting gases 8 1989
 
Gaztech Corporation (1)
5,384,640 Gas sample chamber for use with a source of coherent radiation 16 1993
 
H. Maihak AG (1)
4,641,973 Method and apparatus for measurement of the concentration of a component of a mixture 21 1982
 
Hochiki Kabushiki Kaisha (1)
4,661,320 Gas sensor 40 1984
 
Interox Chemicals Limited (1)
4,680,271 Process and apparatus for analysis 11 1985
 
KYOWA MEDEX CO., LTD. (1)
4,916,058 Method and test composition for determination of hydrogen peroxide 5 1987
 
NIHON KOHDEN CORPORATION (1)
4,998,018 Two-wavelength type respiratory gas concentration measuring apparatus 31 1990
 
OPTICAL FILTER CORPORATION, A CORP. OF NH. (1)
4,323,777 Hydrocarbon gas analyzer 30 1980
 
OZONE STERILIZATION PRODUCTS, INC. (1)
5,167,927 Monitor for ozone, hydrogen peroxide and other gases in fluids 19 1989
 
TEIJIN LIMITED (1)
5,445,792 Optimum hydrogen peroxide vapor sterlization method 77 1994
 
The Secretary of State for Trade and Industry in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland (1)
5,339,155 Optical wavelength modulated long-path gas monitoring apparatus 14 1993
 
Other [Check patent profile for assignment information] (1)
5,081,045 Chemical concentration pressure analyzing apparatus and process 12 1990

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
AMERICAN STERILIZER COMPANY (19)
7,157,046 High capacity flash vapor generation systems 6 2002
7,186,374 Vapor phase decontamination of containers 13 2002
7,803,315 Decontamination of surfaces contaminated with prion-infected material with gaseous oxidizing agents 0 2002
6,936,434 Vapor phase decontamination process biological indicator evaluator resistomer (BIER) vessel 12 2002
6,875,399 Non-dispersive mid-infrared sensor for vaporized hydrogen peroxide 13 2002
7,157,045 Infrared monitor and control for vapor hydrogen peroxide processing techniques 3 2002
7,129,080 Vitro model of priocidal activity 1 2002
7,071,152 Cleaning and decontamination formula for surfaces contaminated with prion-infected material 2 2003
7,217,685 Cleaning and decontamination formula for surfaces contaminated with prion-infected material 3 2006
7,550,122 Decontamination system with air bypass 2 2006
7,700,056 Modular decontamination system 1 2006
7,393,818 Cleaning and decontamination formula for surfaces contaminated with prion-infected material 4 2007
7,919,059 Vaporized hydrogen peroxide decontamination system with concentration adjustment mode 1 2007
7,640,782 Vaporized hydrogen peroxide probe calibration rig 2 2007
7,850,925 Apparatus for removal of vaporized hydrogen peroxide from a region 0 2007
8,007,717 Method and apparatus for decontaminating a region without dehumidification 2 2007
8,357,331 Feed back and dose control of distributed decontamination systems 0 2009
7,988,911 Method for removal of vaporized hydrogen peroxide from a region 0 2010
7,988,920 Device for aerating a region after injection with vaporized hydrogen peroxide 0 2010
 
ETHICON, INC. (4)
7,807,100 Sterilization system and method with temperature-controlled condensing surface 2 2003
7,452,504 Sterilization/disinfection cycle control 0 2004
7,575,716 Sterilization/disinfection cycle control 0 2008
8,658,092 Sterilization system and method and orifice inlet control apparatus therefor 0 2013
 
ABBOTT LABORATORIES (2)
6,318,151 Self-contained sterilant monitoring assembly and method of using same 8 1999
6,532,794 Self-contained sterilant monitoring assembly and method of using same 1 2001
 
CARE BIOPHARMA, LLC (2)
7,090,808 Apparatus for testing sterilization methods and materials 7 2001
6,794,649 Spectrophotometric determination of gas phase compositions 6 2001
 
AXCELIS TECHNOLOGIES, INC. (1)
6,107,634 Decaborane vaporizer 28 1998
 
HUMAN MEDITEK CO., LTD. (1)
7,824,610 Plasma treatment module-equipped sterilization apparatus and sterilization method 0 2003
 
PANASONIC CORPORATION (1)
7,973,924 Target substance sensor and method thereof using a photonic crystal 0 2005
 
STERILUCENT, INC. (1)
8,230,616 Apparatus and method for drying and sterilizing objects in a load 0 2009
 
Steris LLC (1)
7,901,618 Integrated control and distribution system for the decontamination of large volume convoluted configuration spaces 0 2005
 
UNITED TECHNOLOGIES CORPORATION (1)
7,145,052 Decontamination apparatus and methods 6 2004
 
Other [Check patent profile for assignment information] (2)
8,205,416 Method and device for producing and filling containers 0 2004
8,236,240 Method and system for conducting vapor phase decontamination of sealable entities and their contents 0 2007