Composition containing a radioactive component for treatment of vessel wall
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United States of America Patent
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Feb 23, 1999
Grant Date -
N/A
app pub date -
Jan 10, 1997
filing date -
Jan 10, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method and composition for inhibiting restenosis. The composition includes an adhesive or polymeric material having a radioactive component dispersed therethrough. A biologically compatible adhesive including a radioactive material is applied to a vessel region where inhibition of restenosis is desired in a preferred method. In one composition, the radioactive material is admixed with the adhesive. In another composition, the radioactive material is chemically bonded to a polymeric adhesive. The adhesive is preferably cured in place. The radioactive material has a preferred half life of less than six months. In one method, the application of adhesive is followed by stent placement, leaving radioactive adhesive extending beyond both stent ends. The application can include forcing adhesive from a double walled balloon having a porous outer wall.
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