Compositions and methods for modulating cell proliferation using growth factor-polysaccharide binding fusion proteins
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United States of America Patent
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Feb 23, 1999
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app pub date -
Jan 16, 1996
filing date -
Jan 16, 1996
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Abstract
Methods and compositions are provided for in vitro expansion of growth factor dependent cells. Expansion is effected through the use of growth factor conjugates that include a growth factor such as a steel factor and a polysaccharidase substrate binding region. The conjugates are immobilized by binding of the substrate binding region to a substrate of the polysaccharidase in a growth chamber for the cells.
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