Method for sealing tissues with collagen-based sealants
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United States of America Patent
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Feb 23, 1999
Issued Date -
N/A
app pub date -
Mar 5, 1996
filing date -
Jan 29, 1991
priority date (Note) -
Expired
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Abstract
Collagen-based compositions as adhesives and sealants for medical use and preparation thereof are described. Prior to polymerization, soluble or partially fibrillar collagen monomers in solution are chemically modified with an acylating agent, sulfonating agent or a combination of the foregoing. The collagen compositions prepared accordingly can be used as medical adhesives for bonding soft tissues or be made in to a sealant film for a variety of medical uses such as wound closures and tendon wraps for preventing adhesion formation following surgery.
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