Tissue factor compositions and ligands for the specific coagulation of vasculature

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United States of America Patent

PATENT NO 5877289
SERIAL NO

08479733

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Abstract

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Disclosed are various compositions and methods for use in achieving specific blood coagulation. This is exemplified by the specific in vivo coagulation of tumor vasculature, causing tumor regression, through the site-specific delivery of a coagulant using a bispecific antibody.

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Patent Owner(s)

Patent OwnerAddress
SCRIPPS RESEARCH INSTITUTE THE10666 NORTH TORREY PINES ROAD LA JOLLA 92307 CA UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Edgington, Thomas S La Jolla, CA 20 821
Thorpe, Philip E Dallas, TX 83 4023

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