Multivalent single chain antibodies

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United States of America Patent

PATENT NO 5877291
SERIAL NO

08263911

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention discloses multivalent single chain antibodies which have two or more biologically active antigen binding sites. The multivalent single chain antibodies are formed by using a peptide linker to covalently link two or more single chain antibodies, each single chain antibody having a variable light domain linked to a variable heavy chain domain by a peptide linker.

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Patent Owner(s)

Patent OwnerAddress
THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES6011 EXECUTIVE BLVD SUITE 325 ROCKVILLE MD 20852

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gourlie, Brian B Concord, MA 7 278
Mezes, Peter S Oldlyme, CT 31 620

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