Treatment of vascular graft implants with G-CSF
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United States of America Patent
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Mar 9, 1999
Grant Date -
N/A
app pub date -
Sep 19, 1997
filing date -
Sep 19, 1997
priority date (Note) -
Expired
status (Latency Note)
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Abstract
This invention provides methods for enhancing the endothelialization of synthetic vascular grafts by administering to a graft recipient an agent that mobilizes bone marrow-derived CD34.sup.+ cells into the bloodstream, that enhances the adherence to graft surfaces of blood-borne endothelial progenitors, or that stimulates the multiplication of endothelial progenitors that have adhered to the graft surfaces.
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