Combination of fenofibrate and vitamin E, and method of use of same in therapeutic treatments
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United States of America Patent
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Mar 9, 1999
Grant Date -
N/A
app pub date -
Feb 2, 1996
filing date -
Feb 2, 1995
priority date (Note) -
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Abstract
The present invention relates to a novel combination of fenofibrate and a vitamin E substance which comprises: (a) a micronized mixture of fenofibrate with a solid surfactant, and (b) a vitamin E substance selected from the group consisting of tocopherols, their esters with organic acids, and mixtures thereof, wherein: (1) the micronized mixture contains 33 to 200 mg of fenofibrate and the amount of said vitamin E substance represents 100 to 600 IU, and (2) the ratio (Ra) of the amount of fenofibrate, expressed in mg, to the amount of vitamin E substance, expressed in IU, is between 0.33 and 2 mg/IU. It further relates to the method of use of this combination in therapeutic treatments.
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