Surface modified surgical instruments, medical devices, implants, contact lenses and the like
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United States of America Patent
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Mar 23, 1999
Grant Date -
N/A
app pub date -
Sep 25, 1996
filing date -
Sep 25, 1996
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
Improved medical devices and instruments prepared by an improved method of producing hydrophilic, gamma-irradiation induced polymerized and chemically grafted coatings on plastic surfaces of articles adapted for contacting living tissue, the improvement comprising carrying out the graft polymerization in an aqueous solution under specific combinations of the following conditions: (a) monomer concentration in the range of from about 0.1% to about 50%, by weight; (b) total gamma dose in the range of from about 0.001 to less than about 0.50 Mrad; and (c) gamma dose rate in the range of from above about 2,500 to about 10.sup.8 rads/minute.
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