2-oxo-1-azetidine sulfonic acid derivatives as potent .beta.-lactamase inhibitors
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United States of America Patent
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Mar 30, 1999
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N/A
app pub date -
Apr 24, 1997
filing date -
Apr 24, 1997
priority date (Note) -
Expired
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Abstract
A compound of formula (I) ##STR1## wherein R.sub.1 is selected from the group consisting of 2-thienyl, 2-furyl, 2-pyrrolyl, 1-methyl-2-pyrrolyl, 2-amino-1-thiazolyl and 5-isothiazolyl; R.sub.2 is selected from the group consisting of: ##STR2## and M is hydrogen or a pharmaceutically acceptable cation; wherein the oxyimino fragment (.dbd.N--OR.sub.2) in formula (I) is in the `anti` orientation.
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